
Vancomycin exerts its bactericidal effect primarily by which mechanism?
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Get StartedVancomycin exerts its bactericidal effect primarily by which mechanism?
Options:
- Binding D-Ala–D-Ala termini of peptidoglycan precursors
- Inhibiting DNA gyrase
- Blocking the 30S ribosomal subunit
- Disrupting folate synthesis
Correct answer: Binding D-Ala–D-Ala termini of peptidoglycan precursors
Explanation: Vancomycin binds the D‑Ala–D‑Ala terminus of peptidoglycan precursors, preventing cell wall cross‑linking; this bactericidal mechanism targets Gram‑positive bacteria.
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